About a decade ago, a novel technology called the Neuro-Spinal Scaffold for patients with spinal cord injury came to fruition. Today, Cambridge, Mass.-based InVivo Therapeutics’ INSPIRE study is underway to prove the technology’s efficacy.
A bioresorbable polymer scaffold, the Neuro-Spinal Scaffold is designed for implantation at the injury site within a spinal cord contusion, degrading over several weeks. The scaffold is composed of two biocompatible and bioresorbable polymers — Poly(lactic-co-glycolic acid) and Poly-L-Lysine. These polymers are manufactured to create a porous scaffold encouraging cellular attachment and neurite outgrowth.