Growth hormone treatment combined with physical therapy over six months significantly improved sensory function in patients with complete spinal injuries. This research, presented at the European Congress of Endocrinology in Lisbon, is the first human study to investigate the link between spinal injuries and growth hormone deficiency (GHD). These findings could lead to life-improving treatments for patients with spinal injuries.
Although the cause is unknown, over 70% of patients with spinal injuries also produce less growth hormone from the pituitary gland, but few studies have investigated how this impacts recovery. Cell-based studies have shown that growth hormone is involved in regenerative and adaptive processes in neurons and only preliminary studies have examined this in animals or humans. Given the proposed role of growth hormone in neuronal growth and regeneration and that many spinal injury patients exhibit growth hormone deficiency (GHD), therapies restoring growth hormone levels during rehabilitation could enhance recovery.
Original source of this content: https://www.sciencedaily.com/releases/2017/05/170522081046.htm